A variety of issues are often raised in relation to global warming. One is ocean acidification. Increased atmospheric CO₂ increases the amount of CO₂ dissolved in the oceans. CO₂ dissolved in the ocean reacts with water to form carbonic acid resulting in acidification. Ocean surface pH is estimated to have decreased from approximately 8.25 to 8.14 since the beginning of the industrial era, and it is estimated that it will drop by a further 0.14 to 0.5 units by 2100 as the ocean absorbs more CO_2.

From 1960 to 1990 human-caused aerosols likely precipitated this effect. Scientists have stated with 66–90% confidence that the effects of human-caused aerosols, along with volcanic activity, have offset some of global warming, and that greenhouse gases would have resulted in more warming than observed if not for these dimming agents.

Ozone depletion, the steady decline in the total amount of ozone in Earth's stratosphere, is frequently cited in relation to global warming. Although there are areas of linkage, the relationship between the two is not strong.